ADHD medication proves most effective in treating symptoms, new study finds

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In a caller reappraisal article published successful Pediatrics, researchers provided a broad overview of curen options disposable for attention-deficit/hyperactivity upset (ADHD) for children and teen individuals.

 ClareM/Shutterstock.comStudy: Treatments for ADHD successful Children and Adolescents: A Systematic Review. Image Credit: ClareM/


Using a systematic hunt crossed aesculapian databases, they identified 312 involution studies successful 540 published articles that studied ADHD interventions lasting much than 4 weeks for individuals nether nan property of 18 who had been clinically diagnosed pinch ADHD.

The outcomes included wellness and psychosocial indicators, and included studies compared nan involution group pinch active, passive, waitlist, placebo, aliases nary curen groups.

They recovered promising grounds regarding nan increasing readiness of respective treatments that efficaciously dainty symptoms of ADHD for school-aged and young populations and that while medicine continues to beryllium an important shape of therapy, it is associated pinch galore adverse effects.

Medications to dainty ADHD

The reappraisal evaluated various medications for treating ADHD, including accepted stimulants for illustration methylphenidate and amphetamines, arsenic good arsenic nonstimulants.

Studies recovered that accepted stimulants importantly reduced ADHD denotation severity and wide measures but did not notably impact functional impairment.

While methylphenidate formulations improved symptoms and appetite suppression, it was associated pinch much adverse events.

Similarly, amphetamine formulations and norepinephrine reuptake inhibitors (NRIs)  also improved symptoms but suppressed appetite much and had much adverse events, while alpha-agonists were associated pinch less adverse effects.

Nonstimulants importantly improved ADHD symptoms, wide measures, and disruptive behaviors but did not notably impact functional impairment.

Direct comparisons betwixt medications showed varied results, pinch immoderate favoring stimulants complete nonstimulants. However, combining nonstimulants pinch stimulants showed further mini improvements successful symptoms.

Overall, stimulants tended to beryllium much effective successful improving ADHD symptoms and wide measures compared to nonstimulants, pinch immoderate variations successful broadside effects and further benefits erstwhile mixed pinch nonstimulants.

Integrative, alternative, aliases complementary therapies specified arsenic hippotherapy, homeopathy, and acupuncture were not associated pinch improvements successful symptoms of ADHD aliases different result measures.

Behavioral ADHD therapies

Psychosocial interventions importantly improved ADHD symptoms crossed divers approaches, including youth-directed interventions, genitor support programs, and school-based interventions. However, these treatments did not notably impact disruptive behaviors aliases world performance.

Parent support programs besides showed improved broadband scores and disruptive behaviors but not functional impairment.

School interventions did not importantly impact ADHD symptoms but showed imaginable for enhancing world performance.

Cognitive training did not importantly amended ADHD symptoms but was effective successful reducing disruptive behaviors and enhancing broadband measures.

Neurofeedback, peculiarly targeting EEG markers, importantly improved ADHD symptoms pinch minimal heterogeneity, though its effect connected disruptive behaviors and functional impairment was inconclusive.

Overall, these findings propose the efficacy of psychosocial interventions successful alleviating ADHD symptoms successful youth, pinch variations successful effectiveness crossed different approaches and outcomes.

Combining behavioral treatments and medication

The reviewers recovered immoderate studies that mixed psychosocial treatments pinch medicine (primarily atomoxetine aliases stimulants).

Cognitive behavioral therapy, behavioral therapy, humanistic interventions, solution-focused therapy, and multimodal psychosocial treatments were included arsenic behavioral treatments.

These studies examined nan effect of further psychosocial curen compared to medicine unsocial and did not see placebo aliases nary curen arms.

There was small grounds that mixed therapy improved ADHD symptoms and different outcomes.

Other cardinal findings

Nutrition interventions were mostly placebo-controlled and included supplements and different dietary treatments, which were often administered successful summation to stimulants.

There were nary supplements, including omega-3, which were associated pinch accordant improvements successful outcomes. However, nutritional interventions were mostly recovered to amended symptoms of ADHD and associated disruptive behaviors without expanding adverse effects.

The study recovered constricted grounds connected whether different types of ADHD aliases coexisting psychiatric conditions power curen outcomes. Long-term follow-up data, particularly beyond 12 months, were sparse crossed interventions.

Studies, including those examining nan effect of multimodal treatments, did not show sustained effects beyond 12 months crossed various interventions, isolated from for immoderate medicine trials.


The reappraisal encompasses a broad study of ADHD treatments, highlighting nan effectiveness of divers interventions crossed aggregate domains.

Medications, including stimulants and nonstimulants, show important improvements successful ADHD symptoms, pinch mean to precocious spot of evidence. Psychosocial treatments, neurofeedback, and nutritional interventions show varied effectiveness, often pinch little spot of evidence.

Combining treatments was not recovered to consistently heighten outcomes. There is simply a dearth of studies connected semipermanent effects and comparative effectiveness, emphasizing nan request for much investigation to pass curen decisions and amended diligent care.

The authors acknowledged that nan scope of their reappraisal was constricted by their eligibility criteria, excluding immoderate earlier studies, psychosocial interventions, and studies pinch smaller sample sizes.

Future investigation is required to analyse nan comparative effectiveness of various treatments pinch web meta-analysis approaches.

Journal reference:

  • Peterson, B.S., Trampush, J., Maglione, M., Bolshakova, M., Rozelle, M., Miles, J., Pakdaman, S., Brown, M., Yagyu, S., Motala, A., Hempel, S. (2024) Treatments for ADHD successful children and adolescents: a systematic review. Pediatrics. doi: